Warning: This data is provided for information purpose only. You should not start or stop any medication without consulting your care giver.
Use the Health Monitor application at http://www.healthsupportsystems.com to search for a drug by brand, generic or symptom
ADVICOR
Active Ingredients
NIACIN,LOVASTATIN
Inctive Ingredients
hypromellose,povidone,stearic acid,polyethylene glycol,titanium dioxide,polysorbate 80,synthethic red and yellow iron oxides
Usage
ADVICOR is a fixed-dose combination product and is not indicated for initial therapy (see DOSAGE AND ADMINISTRATION). Therapy with lipid-altering agents should be only one component of multiple risk-factor intervention in individuals at significantly increased risk for atherosclerotic vascular disease due to hypercholesterolemia. Initial medical therapy is indicated with a single agent as an adjunct to diet when the response to a diet restricted in saturated fat and cholesterol and other nonpharmacologic measures alone has been inadequate (see also Table 7 and the NCEP treatment guidelines1).
ADVICOR is indicated for the treatment of primary hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia (Frederickson Types IIa and IIb; Table 6) in:
? Patients treated with lovastatin who require further TG-lowering or HDL-raising who may benefit from having niacin added to their regimen
? Patients treated with niacin who require further LDL-lowering who may benefit from having lovastatin added to their regimen.
| Lipid Elevations | |||||
| Type | Lipoproteins Elevated | Major | Minor | ||
TC = total cholesterol; TG = triglycerides; LDL = low-density lipoprotein; VLDL = very low-density lipoprotein; IDL = intermediate-density lipoprotein ?? = increased or no change | |||||
| I (rare) | Chylomicrons | TG | ??TC | ||
| IIa | LDL | TC | - | ||
| IIb | LDL,VLDL | TC | TG | ||
| III (rare) | IDL | TC/TG | - | ||
| IV | VLDL | TG | ??TC | ||
| V (rare) | Chylomicrons, VLDL | TG | ??TC | ||